Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers
نویسندگان
چکیده
منابع مشابه
Prokinetic effects of mirtazapine on gastrointestinal transit.
Mirtazapine is a noradrenergic and specific serotonergic antidepressant. The aim of this study was to investigate the effects of mirtazapine on gastrointestinal motility in dogs, including solid gastric emptying, antral and small intestinal contractions, and small intestinal and colonic transit. Six dogs were implanted with two cannulas located at the duodenum and the ascending colon; another s...
متن کاملEffect of Epidural Anesthesia with Lidocaine and Bupivacaine on Gastrointestinal Transit Time in Healthy Dogs
Objective- To evaluate the effect of epidural anesthesia with lidocaine and bupivacaine on transit time of barium sulfate contrast medium through gastrointestinal (GI) tracts in healthy dogs. Design- Prospective, randomized experimental study. Animals-Five healthy mixed breed male dogs with 19.2±7.8 months age and 19.9±3.3 kg weight Procedure- The animals received one of the treatments of sa...
متن کاملEffect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers.
Chloride channels modulate gastrointestinal neuromuscular functions in vitro. Lubiprostone, a selective type 2 chloride channel (ClC-2) activator, induces intestinal secretion and has been shown to relieve constipation in clinical trials; however, the effects of lubiprostone on gastric function and whole gut transit in humans are unclear. Our aim was to compare the effects of the selective ClC-...
متن کاملeffect of sub-grid scales on large eddy simulation of particle deposition in a turbulent channel flow
چکیده ندارد.
15 صفحه اولEffect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers.
BACKGROUND Yacon is a root crop which contains high amounts of fructooligosaccharides (FOS). The aim of this study was to investigate the effects of yacon syrup on colon transit time in healthy volunteers. METHODS In a placebo-controlled, double-blind study yacon was administered to 16 healthy individuals (8 males, 8 females) in a dose of 20 g daily (equal to 6.4 g FOS) in a 2-week crossover ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 1998
ISSN: 0017-5749
DOI: 10.1136/gut.42.4.511